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RAB11B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q15907
Clone Names 100324172
Peptide ID 100324172
Additional Information
Gene ID 9230
Other Names Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB11B
Synonyms YPT3
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage- gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Cellular Location Recycling endosome membrane; Lipid-anchor; Cytoplasmic side Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus
Research Areas
Citations (0)

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The Ras superfamily of small GTP-binding proteins, whichincludes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (seeMIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508)families, is involved in controlling a diverse set of essentialcellular functions. The Rab family, including RAB11B, appears toplay a critical role in regulating exocytotic and endocytoticpathways (summary by Zhu et al., 1994 [PubMed 7811277]).[suppliedby OMIM].


Agop-Nersesian, C., et al. PLoS Pathog. 6 (7), E1001029 (2010) :Silvis, M.R., et al. Mol. Biol. Cell 20(8):2337-2350(2009)Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)Scapin, S.M., et al. J. Struct. Biol. 154(3):260-268(2006)Khvotchev, M.V., et al. J. Neurosci. 23(33):10531-10539(2003)

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$ 80.00
Cat# BP12943b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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