|Other Names||Serine/arginine-rich splicing factor 11, Arginine-rich 54 kDa nuclear protein, p54, Splicing factor, arginine/serine-rich 11, SRSF11, SFRS11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May function in pre-mRNA splicing.|
|Cellular Location||Nucleus. Note=Colocalizes with spliceosome components|
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This gene encodes 54-kD nuclear protein that contains anarginine/serine-rich region similar to segments found in pre-mRNAsplicing factors. Although the function of this protein is not yetknown, structure and immunolocalization data suggest that it mayplay a role in pre-mRNA processing. Alternative splicing results inmultiple transcript variants encoding different proteins. Inaddition, a pseudogene of this gene has been found on chromosome12.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)Casado, P., et al. J Proteomics 71(6):592-600(2009)Shepard, P.J., et al. Genome Biol. 10 (10), 242 (2009) :Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
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