ZHX3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H4I2 |
---|---|
Clone Names | 100324176 |
Gene ID | 23051 |
---|---|
Other Names | Zinc fingers and homeoboxes protein 3, Triple homeobox protein 1, Zinc finger and homeodomain protein 3, ZHX3, KIAA0395, TIX1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ZHX3 |
---|---|
Synonyms | KIAA0395, TIX1 |
Function | Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12659632} |
Tissue Location | Widely expressed. High expression in kidney. Expressed during osteogenic differentiation |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the zinc fingers andhomeoboxes (ZHX) gene family. The encoded protein contains twoC2H2-type zinc fingers and five homeodomains and forms a dimer withitself or with zinc fingers and homeoboxes family member 1. In thenucleus, the dimerized protein interacts with the A subunit of theubiquitous transcription factor nuclear factor-Y and may functionas a transcriptional repressor.
References
Liu, G., et al. J. Biol. Chem. 281(51):39681-39692(2006)Lim, J., et al. Cell 125(4):801-814(2006)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)Kawata, H., et al. Gene 323, 133-140 (2003) :Yamada, K., et al. Biochem. J. 373 (PT 1), 167-178 (2003) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.