|Other Names||Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+), Amino acid transporter ATB0+, Solute carrier family 6 member 14, SLC6A14|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis.|
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This gene encodes a member of the solute carrier family 6.Members of this family are sodium and chloride dependentneurotransmitter transporters. The encoded protein transports bothneutral and cationic amino acids. This protein may also function asa beta-alanine carrier. Mutations in this gene may be associatedwith X-linked obesity. A pseudogene of this gene is found onchromosome X.
Bailey, S.D., et al. Diabetes Care (2010) In press :Corpeleijn, E., et al. Obesity (Silver Spring) 18(7):1369-1377(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Anderson, C.M., et al. J. Physiol. (Lond.) 586 (PT 17), 4061-4067 (2008) :Eriksson, A., et al. BMC Gastroenterol 8, 34 (2008) :
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