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SRP9 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P49458 |
|---|---|
| Clone Names | 100324227 |
| Gene ID | 6726 |
|---|---|
| Other Names | Signal recognition particle 9 kDa protein, SRP9, SRP9 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SRP9 |
|---|---|
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (PubMed:11089964). The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
References
Mary, C., et al. RNA 16(5):969-979(2010)Rho, J.H., et al. J. Proteome Res. 7(7):2959-2972(2008)Maity, T.S., et al. Biochemistry 45(50):14955-14964(2006)Andersen, J.S., et al. Nature 433(7021):77-83(2005)Weichenrieder, O., et al. Nature 408(6809):167-173(2000)
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