PITPNB Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P48739 |
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Clone Names | 100405022 |
Gene ID | 23760 |
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Other Names | Phosphatidylinositol transfer protein beta isoform, PI-TP-beta, PtdIns transfer protein beta, PtdInsTP beta, PITPNB |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PITPNB |
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Function | Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (PubMed:10531358, PubMed:18636990, PubMed:20332109). Also catalyzes the transfer of sphingomyelin (By similarity). Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function (PubMed:20332109). |
Cellular Location | Golgi apparatus {ECO:0000250|UniProtKB:P53811}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P53812}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P53812} |
Tissue Location | Widely expressed in various tissues including brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is found in thecytoplasm, where it catalyzes the transfer of phosphatidylinositoland phosphatidylcholine between membranes.
References
Carvou, N., et al. J. Cell. Sci. 123 (PT 8), 1262-1273 (2010) :Morgan, C.P., et al. Biochem. J. 398(3):411-421(2006)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Segui, B., et al. Biochem. J. 366 (PT 1), 23-34 (2002) :
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