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PIGV Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NUD9 |
|---|---|
| Clone Names | 100405224 |
| Gene ID | 55650 |
|---|---|
| Other Names | GPI mannosyltransferase 2, 241-, GPI mannosyltransferase II, GPI-MT-II, Phosphatidylinositol-glycan biosynthesis class V protein, PIG-V, PIGV |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PIGV |
|---|---|
| Function | Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycosylphosphatidylinositol (GPI) is a complex glycolipidthat anchors many proteins to the cell surface. The biosyntheticpathway of GPI is mediated by sequential addition of sugars andother components to phosphatidylinositol. PIGV adds the secondmannose to the GPI core (Kang et al., 2005 [PubMed15623507]).
References
Krawitz, P.M., et al. Nat. Genet. 42(10):827-829(2010)Kang, J.Y., et al. J. Biol. Chem. 280(10):9489-9497(2005)Fabre, A.L., et al. FEBS J. 272(5):1160-1168(2005)Kinoshita, T., et al. Curr Opin Chem Biol 4(6):632-638(2000)
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