SEMA4C Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9C0C4 |
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Clone Names | 100405237 |
Gene ID | 54910 |
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Other Names | Semaphorin-4C, SEMA4C, KIAA1739, SEMAI |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SEMA4C |
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Synonyms | KIAA1739, SEMAI |
Function | Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. |
Cellular Location | Postsynaptic density membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
References
Wu, H., et al. Eur. J. Cell Biol. 86(6):331-344(2007)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Inagaki, S., et al. J. Biol. Chem. 276(12):9174-9181(2001)Ohoka, Y., et al. Biochem. Biophys. Res. Commun. 280(1):237-243(2001)Wang, L.H., et al. J. Biol. Chem. 274(20):14137-14146(1999)
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