CTSR3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86XQ3 |
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Clone Names | 91208054 |
Gene ID | 347732 |
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Other Names | Cation channel sperm-associated protein 3, CatSper3, Ca(v)-like protein, One-repeat calcium channel-like protein, CATSPER3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CATSPER3 |
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Function | Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. |
Cellular Location | Cell projection, cilium, flagellum membrane {ECO:0000250|UniProtKB:Q80W99}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q80W99} |
Tissue Location | Testis-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization (By similarity).
References
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Qi, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(4):1219-1223(2007)Clapham, D.E., et al. Pharmacol. Rev. 57(4):451-454(2005)Lobley, A., et al. Reprod. Biol. Endocrinol. 1, 53 (2003) :Arias, J.M., et al. Biochem. Biophys. Res. Commun. 303(1):31-36(2003)
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