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CTSR3 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86XQ3
Clone Names 91208054
Peptide ID 91208054
Additional Information
Gene ID 347732
Other Names Cation channel sperm-associated protein 3, CatSper3, Ca(v)-like protein, One-repeat calcium channel-like protein, CATSPER3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CATSPER3
Function Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
Cellular Location Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail
Tissue Location Testis-specific.
Research Areas
Citations (0)

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Background

Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization (By similarity).

References

Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Qi, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(4):1219-1223(2007)Clapham, D.E., et al. Pharmacol. Rev. 57(4):451-454(2005)Lobley, A., et al. Reprod. Biol. Endocrinol. 1, 53 (2003) :Arias, J.M., et al. Biochem. Biophys. Res. Commun. 303(1):31-36(2003)

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$ 80.00
Cat# BP13012b
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