|Other Names||Retbindin, RTBDN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in retina.|
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Provided below are standard protocols that you may find useful for product applications.
Using expressed sequence tag (EST) analysis of unamplified cDNA libraries generated from human retina, Wistow et al. (2002) identified an abundant novel open reading frame that encoded a 229 residue protein with a predicted molecular mass of 24.6 kD. The corresponding gene, which they named retbindin (RTBDN), shows modest sequence homology to riboflavin binding proteins of egg laying vertebrates, and more distant similarity to mammalian folate receptors. Analysis of the 5 prime ends of multiple RTBDN clones identified splice variants that suggested the presence of multiple promoters. Northern blot analysis of rhesus monkey tissues showed retina specific expression of a 1.2 kb RTBDN transcript.
Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :
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