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C21orf59 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P57076 |
|---|---|
| Clone Names | 100406030 |
| Gene ID | 56683 |
|---|---|
| Other Names | UPF0769 protein C21orf59, C21orf59, C21orf48 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CFAP298 (HGNC:1301) |
|---|---|
| Synonyms | C21orf48, C21orf59 |
| Function | Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0A1L8HCK2}. Note=Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization {ECO:0000250|UniProtKB:Q5U3Z0} |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of the C21orf59 protein remains unknown.
References
Denoeud, F., et al. Genome Res. 17(6):746-759(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
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