|Other Names||Phosphatidylinositol N-acetylglucosaminyltransferase subunit H, Phosphatidylinositol-glycan biosynthesis class H protein, PIG-H, PIGH|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an endoplasmic reticulum associatedprotein that is involved in glycosylphosphatidylinositol(GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found onmany blood cells and which serves to anchor proteins to the cellsurface. The protein encoded by this gene is a subunit of the GPIN-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc tophosphatidylinositol (PI) on the cytoplasmic side of theendoplasmic reticulum.
Lamesch, P., et al. Genomics 89(3):307-315(2007)Kinoshita, T., et al. Curr Opin Chem Biol 4(6):632-638(2000)Watanabe, R., et al. EMBO J. 17(4):877-885(1998)Watanabe, R., et al. J. Biol. Chem. 271(43):26868-26875(1996)Ware, R.E., et al. Blood 83(12):3753-3757(1994)
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