|Other Names||Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14, Apoptosis regulator Bcl-G, BCL2L14, BCLG|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1304a was selected from the region of human Bcl-G BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in apoptosis.|
|Cellular Location||Cytoplasm. Isoform 2: Endomembrane system. Note=Predominantly localized to cytosolic organelles|
|Tissue Location||Isoform 1 is widely expressed. Isoform 2 is testis-specific.|
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Provided below are standard protocols that you may find useful for product applications.
Bcl-G belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of Bcl-G has been shown to induce apoptosis in cells.
Ozalp, S.S., et al., Eur J Gynaecol Oncol 23(5):419-422 (2002).Guo, B., et al., J. Biol. Chem. 276(4):2780-2785 (2001).
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