Bcl-G BH3 Domain Antibody Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BZR8 |
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Clone Names | 2011405 |
Gene ID | 79370 |
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Other Names | Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14, Apoptosis regulator Bcl-G, BCL2L14, BCLG |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1304a was selected from the region of human Bcl-G BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BCL2L14 |
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Synonyms | BCLG |
Function | Plays a role in apoptosis. |
Cellular Location | Cytoplasm. [Isoform 2]: Endomembrane system. Note=Predominantly localized to cytosolic organelles |
Tissue Location | Isoform 1 is widely expressed. Isoform 2 is testis- specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Bcl-G belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of Bcl-G has been shown to induce apoptosis in cells.
References
Ozalp, S.S., et al., Eur J Gynaecol Oncol 23(5):419-422 (2002).Guo, B., et al., J. Biol. Chem. 276(4):2780-2785 (2001).
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