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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GLYAT Antibody (Center) Blocking peptide   

GLYAT Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6IB77
Clone Names 110111024
Peptide ID 110111024
Additional Information
Gene ID 10249
Other Names Glycine N-acyltransferase, Acyl-CoA:glycine N-acyltransferase, AAc, Aralkyl acyl-CoA N-acyltransferase, Aralkyl acyl-CoA:amino acid N-acyltransferase, Benzoyl-coenzyme A:glycine N-acyltransferase, Glycine N-benzoyltransferase, HRP-1(CLP), GLYAT, ACGNAT, CAT, GAT
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLYAT
Synonyms ACGNAT, CAT, GAT
Function Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Cellular Location Mitochondrion.
Tissue Location Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers.
Research Areas
Citations (0)

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Background

The glycine-N-acyltransferase protein conjugates glycinewith acyl-CoA substrates in the mitochondria. The protein isthought to be important in the detoxification of endogenous andxenobiotic acyl-CoA's. Two transcript variants encoding differentisoforms have been found for this gene.

References

Yamamoto, A., et al. Drug Metab. Pharmacokinet. 24(1):114-117(2009)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)van der Westhuizen, F.H., et al. J. Biochem. Mol. Toxicol. 14(2):102-109(2000)Mawal, Y., et al. J. Pediatr. 130(6):1003-1007(1997)Merkler, D.J., et al. Arch. Biochem. Biophys. 330(2):430-434(1996)

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$ 80.00
Cat# BP13064c
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