|Other Names||Ligand of Numb protein X 2, Numb-binding protein 2, PDZ domain-containing RING finger protein 1, LNX2, PDZRN1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
LNX2 (Ligand of numb-protein X 2) is a multimodular protein that binds to NUMB via the NPXY motif. It may serve as a molecular scaffold that localizes unrelated, interacting proteins, such as NUMB, to specific subcellular sites.
Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009)Sullivan, P.F., et al. Mol. Psychiatry 13(6):570-584(2008)Dunham, A., et al. Nature 428(6982):522-528(2004)Rice, D.S., et al. Mol. Cell. Neurosci. 18(5):525-540(2001)
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