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ADSS Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P30520 |
|---|---|
| Clone Names | 90429012 |
| Gene ID | 159 |
|---|---|
| Other Names | Adenylosuccinate synthetase isozyme 2 {ECO:0000255|HAMAP-Rule:MF_03127}, AMPSase 2 {ECO:0000255|HAMAP-Rule:MF_03127}, AdSS 2 {ECO:0000255|HAMAP-Rule:MF_03127}, 6344 {ECO:0000255|HAMAP-Rule:MF_03127}, Adenylosuccinate synthetase, acidic isozyme {ECO:0000255|HAMAP-Rule:MF_03127}, Adenylosuccinate synthetase, liver isozyme {ECO:0000255|HAMAP-Rule:MF_03127}, L-type adenylosuccinate synthetase {ECO:0000255|HAMAP-Rule:MF_03127}, IMP--aspartate ligase 2 {ECO:0000255|HAMAP-Rule:MF_03127}, ADSS {ECO:0000255|HAMAP-Rule:MF_03127} |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13092b was selected from the C-term region of ADSS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ADSS2 (HGNC:292) |
|---|---|
| Function | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
| Cellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03127}. Mitochondrion {ECO:0000250|UniProtKB:A4Z6H1}. Note=Partially associated with particulate fractions |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the enzyme adenylosuccinate synthetasewhich catalyzes the first committed step in the conversion ofinosine monophosphate to adenosine monophosphate. A pseudogene ofthis gene is found on chromosome 17.
References
Sivendran, S., et al. Protein Sci. 17(7):1162-1174(2008)Zhang, F., et al. BMC Med. Genet. 9, 119 (2008) :Zhang, F., et al. Behav Brain Funct 4, 39 (2008) :Sun, H., et al. Mol. Cell. Biochem. 269 (1-2), 85-94 (2005) :Stepinski, J., et al. Kidney Int. 50(4):1195-1201(1996)
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