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LSM12 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q3MHD2 |
|---|---|
| Clone Names | 91218192 |
| Gene ID | 124801 |
|---|---|
| Other Names | Protein LSM12 homolog, LSM12 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13111b was selected from the C-term region of LSM12. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LSM12 |
|---|---|
| Function | Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein (PubMed:34362892). Confers NAADP sensitivity to the two pore channel complex (TPCs) by acting as TPC accessory protein necessary for NAADP-evoked Ca(2+) release (PubMed:34362892). |
| Cellular Location | Cytoplasm. Note=Colocalizes with TPCN2. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LSM12 belongs to the LSM12 family. The exact function of LSM12 is not known.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Albrecht, M., et al. FEBS Lett. 569 (1-3), 18-26 (2004) :
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