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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GRIK3 Antibody (N-term) Blocking Peptide   

GRIK3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13003
Clone Names 100318114
Peptide ID 100318114
Additional Information
Gene ID 2899
Other Names Glutamate receptor ionotropic, kainate 3, GluK3, Excitatory amino acid receptor 5, EAA5, Glutamate receptor 7, GluR-7, GluR7, GRIK3, GLUR7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13113a was selected from the N-term region of GRIK3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRIK3
Synonyms GLUR7
Function Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Glutamate receptors are the predominant excitatoryneurotransmitter receptors in the mammalian brain and are activatedin a variety of normal neurophysiologic processes. This geneproduct belongs to the kainate family of glutamate receptors, whichare composed of four subunits and function as ligand-activated ionchannels. It is not certain if the subunit encoded by this gene issubject to RNA editing as the other 2 family members (GRIK1 andGRIK2). A Ser310Ala polymorphism has been associated withschizophrenia, and there are conflicting reports of its associationwith the pathogenesis of delirium tremens in alcoholics. [providedby RefSeq].


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Luciano, M., et al. Behav. Genet. 40(4):518-532(2010)Kilic, G., et al. Psychiatry Res 175 (1-2), 43-46 (2010) :Gill, M.B., et al. J. Biol. Chem. 284(21):14503-14512(2009)Ahmad, Y., et al. World J. Biol. Psychiatry 10(4):330-333(2009)

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$ 80.00
Cat# BP13113a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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