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PFDN5 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99471
Clone Names 100324077
Peptide ID 100324077
Additional Information
Gene ID 5204
Other Names Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1, PFDN5, MM1, PFD5
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13122c was selected from the Center region of PFDN5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PFDN5
Synonyms MM1, PFD5
Function Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Cellular Location Isoform 1: Nucleus. Isoform 3: Nucleus.
Tissue Location Highly expressed in pancreas and skeletal muscle and moderately in other tissues
Research Areas
Citations (0)

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This gene encodes a member of the prefoldin alpha subunitfamily. The encoded protein is one of six subunits of prefoldin, amolecular chaperone complex that binds and stabilizes newlysynthesized polypeptides, thereby allowing them to fold correctly.The complex, consisting of two alpha and four beta subunits, formsa double beta barrel assembly with six protruding coiled-coils. Theencoded protein may also repress the transcriptional activity ofthe proto-oncogene c-Myc. Alternatively spliced transcript variantsencoding different isoforms have been described. [provided byRefSeq].


Ma, H.C., et al. J. Biomed. Sci. 15(4):417-425(2008)Yoshida, T., et al. Exp. Cell Res. 314(6):1217-1228(2008)Lubyova, B., et al. J. Biol. Chem. 282(44):31944-31953(2007)Hagio, Y., et al. J. Cell. Biochem. 97(1):145-155(2006)Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)

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$ 80.00
Cat# BP13122c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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