|Other Names||G-protein coupled receptor-associated sorting protein 2, GASP-2, GPRASP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13135a was selected from the N-term region of GPRASP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in regulation of a variety of G-protein coupled receptors.|
|Tissue Location||Expressed in the brain.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of a familythat regulates the activity of G protein-coupled receptors (GPCRs).The encoded protein has been shown to be capable of interactingwith several GPCRs, including the M1 muscarinic acetylcholinereceptor and the calcitonin receptor. Several transcript variantsencoding the same protein have been found for this gene. [providedby RefSeq].
Piton, A., et al. Mol. Psychiatry (2010) In press :Horn, S.C., et al. J Neural Transm 113(8):1081-1090(2006)Goehler, H., et al. Mol. Cell 15(6):853-865(2004)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)Simonin, F., et al. J. Neurochem. 89(3):766-775(2004)
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