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CASP6 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P55212
Clone Names 4093005
Peptide ID 4093005
Additional Information
Gene ID 839
Other Names Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1313b was selected from the C-term region of human CASP6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP6
Synonyms MCH2
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.


Schmeck, B., et al., Infect. Immun. 72(9):4940-4947 (2004).Mendez, E., et al., J. Virol. 78(16):8601-8608 (2004).MacLachlan, T.K., et al., Proc. Natl. Acad. Sci. U.S.A. 99(14):9492-9497 (2002).Sordet, O., et al., Leukemia 16(8):1569-1570 (2002).LeBlanc, A., et al., J. Biol. Chem. 274(33):23426-23436 (1999).

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$ 80.00
Cat# BP1313b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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