|Other Names||Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va, COX5A|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13154a was selected from the N-term region of COX5A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.|
|Cellular Location||Mitochondrion inner membrane.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Cytochrome c oxidase (COX) is the terminal enzyme of themitochondrial respiratory chain. It is a multi-subunit enzymecomplex that couples the transfer of electrons from cytochrome c tomolecular oxygen and contributes to a proton electrochemicalgradient across the inner mitochondrial membrane. The complexconsists of 13 mitochondrial- and nuclear-encoded subunits. Themitochondrially-encoded subunits perform the electron transfer ofproton pumping activities. The functions of the nuclear-encodedsubunits are unknown but they may play a role in the regulation andassembly of the complex. This gene encodes the nuclear-encodedsubunit Va of the human mitochondrial respiratory chain enzyme. Apseudogene COX5AP1 has been found in chromosome 14q22. [provided byRefSeq].
Chen, Z.X., et al. Cell Death Differ. 17(3):408-420(2010)Fornuskova, D., et al. Biochem. J. 428(3):363-374(2010)Uddin, M., et al. BMC Evol. Biol. 8, 8 (2008) :Williams, S.L., et al. J. Biol. Chem. 279(9):7462-7469(2004)Hofmann, S., et al. Cytogenet. Cell Genet. 83 (3-4), 226-227 (1998) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.