|Other Names||Protein Mis18-alpha, FAPP1-associated protein 1, MIS18A, C21orf45, C21orf46, FASP1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13158c was selected from the Center region of C21orf45. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C21orf45, C21orf46, FASP1|
|Function||Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.|
|Cellular Location||Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin|
|Tissue Location||Detected in testis.|
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Provided below are standard protocols that you may find useful for product applications.
C21orf45 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Birlea, S.A., et al. J. Invest. Dermatol. 130(3):798-803(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Fujita, Y., et al. Dev. Cell 12(1):17-30(2007)Ye, X.X., et al. Mol. Cell. Biochem. 271 (1-2), 151-158 (2005) :Gardiner, K., et al. Genomics 79(6):833-843(2002)
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