|Other Names||Amelogenin, X isoform, AMELX, AMG, AMGX|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13169a was selected from the N-term region of AMELX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the amelogenin family ofextracellular matrix proteins. Amelogenins are involved inbiomineralization during tooth enamel development. Mutations inthis gene cause X-linked amelogenesis imperfecta. Alternativesplicing results in multiple transcript variants encoding differentisoforms.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Almqvist, S., et al. J Mater Sci Mater Med 21(3):947-954(2010)Lee, S.K., et al. J. Dent. Res. 89(1):46-50(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Tomas, C., et al. Forensic Sci Int Genet 3(1):1-6(2008)
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