SSR2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P43308 |
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Clone Names | 100324119 |
Gene ID | 6746 |
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Other Names | Translocon-associated protein subunit beta, TRAP-beta, Signal sequence receptor subunit beta, SSR-beta, SSR2, TRAPB |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13170b was selected from the C-term region of SSR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SSR2 |
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Synonyms | TRAPB |
Function | TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. |
Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The signal sequence receptor (SSR) is a glycosylatedendoplasmic reticulum (ER) membrane receptor associated withprotein translocation across the ER membrane. The SSR consists of 2subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kDglycoprotein (beta-SSR or SSR2). The human beta-signal sequencereceptor gene (SSR2) maps to chromosome bands 1q21-q23. [providedby RefSeq].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sikorska, M., et al. J. Neurosci. Res. 86(8):1680-1693(2008)Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)Wang, L., et al. FEBS Lett. 457(3):316-322(1999)Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)
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