|Other Names||60S ribosomal protein L34, RPL34|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13207c was selected from the Center region of RPL34. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L34E family of ribosomal proteins. It is located in thecytoplasm. This gene originally was thought to be located at 17q21,but it has been mapped to 4q. Transcript variants derived fromalternative splicing, alternative transcription initiation sites,and/or alternative polyadenylation exist; these variants encode thesame protein. As is typical for genes encoding ribosomal proteins,there are multiple processed pseudogenes of this gene dispersedthrough the genome.
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Andersen, J.S., et al. Nature 433(7021):77-83(2005)Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :Mazumder, B., et al. Cell 115(2):187-198(2003)
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