|Other Names||Monocarboxylate transporter 10, MCT 10, Aromatic amino acid transporter 1, Solute carrier family 16 member 10, T-type amino acid transporter 1, SLC16A10, MCT10, TAT1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13235b was selected from the C-term region of SLC16A10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Basolateral cell membrane|
|Tissue Location||Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart|
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Provided below are standard protocols that you may find useful for product applications.
SLC16A10 is a member of a family of plasma membrane aminoacid transporters that mediate the Na(+)-independent transport ofaromatic amino acids across the plasma membrane.
Loubiere, L.S., et al. Placenta 31(4):295-304(2010)Friesema, E.C., et al. Mol. Endocrinol. 22(6):1357-1369(2008)Broer, S. Physiol. Rev. 88(1):249-286(2008)Park, S.Y., et al. Arch. Pharm. Res. 28(4):421-432(2005)Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)
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