|Other Names||Olfactory receptor 8J1, Olfactory receptor OR11-183, OR8J1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13259a was selected from the N-term region of OR8J1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Olfactory receptors interact with odorant molecules in thenose, to initiate a neuronal response that triggers the perceptionof a smell. The olfactory receptor proteins are members of a largefamily of G-protein-coupled receptors (GPCR) arising from singlecoding-exon genes. Olfactory receptors share a 7-transmembranedomain structure with many neurotransmitter and hormone receptorsand are responsible for the recognition and G protein-mediatedtransduction of odorant signals. The olfactory receptor gene familyis the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism isindependent of other organisms.
Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004)Fuchs, T., et al. Genomics 80(3):295-302(2002)
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