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TRIM54 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BYV2 |
|---|---|
| Clone Names | 100408340 |
| Gene ID | 57159 |
|---|---|
| Other Names | Tripartite motif-containing protein 54, Muscle-specific RING finger protein, MuRF, Muscle-specific RING finger protein 3, MuRF-3, MuRF3, RING finger protein 30, TRIM54, MURF, MURF3, RNF30 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13292a was selected from the N-term region of TRIM54. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TRIM54 |
|---|---|
| Synonyms | MURF, MURF3, RNF30 |
| Function | May bind and stabilize microtubules during myotubes formation. |
| Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity). |
| Tissue Location | Specifically expressed in heart and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene contains a RING fingermotif and is highly similar to the ring finger proteins RNF28/MURF1and RNF29/MURF2. In vitro studies demonstrated that this protein,RNF28, and RNF29 form heterodimers, which may be important for theregulation of titin kinase and microtubule-dependent signalpathways in striated muscles. Alternatively spliced transcriptvariants encoding distinct isoforms have been reported. [providedby RefSeq].
References
Centner, T., et al. J. Mol. Biol. 306(4):717-726(2001)Spencer, J.A., et al. J. Cell Biol. 150(4):771-784(2000)
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