|Other Names||Excitatory amino acid transporter 5, Retinal glutamate transporter, Solute carrier family 1 member 7, SLC1A7, EAAT5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13331c was selected from the Center region of SLC1A7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed primarily in retina. Detectable in liver, heart, muscle and brain|
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Provided below are standard protocols that you may find useful for product applications.
Transports L-glutamate; the L-glutamate uptake is sodium-and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
Bailey, S.D., et al. Diabetes Care (2010) In press :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Boehmer, C., et al. Biochem. Biophys. Res. Commun. 329(2):738-742(2005)
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