Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
C14orf104 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NVR5 |
|---|---|
| Clone Names | 100416179 |
| Gene ID | 55172 |
|---|---|
| Other Names | Protein kintoun, Dynein assembly factor 2, axonemal, DNAAF2, C14orf104, KTU |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13345a was selected from the N-term region of C14orf104. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DNAAF2 {ECO:0000255|HAMAP-Rule:MF_03069} |
|---|---|
| Function | Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. |
| Cellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03069, ECO:0000269|PubMed:19052621}. Dynein axonemal particle {ECO:0000250|UniProtKB:B1H1W9}. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia. {ECO:0000255|HAMAP-Rule:MF_03069} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a highly conserved protein involved inthe preassembly of dynein arm complexes which power cilia. Thesecomplexes are found in some cilia and are assembled in thecytoplasm prior to transport for cilia formation. Mutations in thisgene have been associated with primary ciliary dyskinesia. Multipletranscript variants encoding different isoforms have been found forthis gene.
References
Omran, H., et al. Nature 456(7222):611-616(2008)Heilig, R., et al. Nature 421(6923):601-607(2003)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
