KIAA0319L Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IZA0 |
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Clone Names | 100416266 |
Gene ID | 79932 |
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Other Names | Dyslexia-associated protein KIAA0319-like protein, KIAA0319L, KIAA1837 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13352b was selected from the C-term region of KIAA0319L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | KIAA0319L (HGNC:30071) |
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Function | Possible role in axon guidance through interaction with RTN4R. |
Cellular Location | Cytoplasmic granule membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Traffics from the plasma membrane to the trans-Golgi network. |
Tissue Location | Expressed in cortical neurons in the brain cortex (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a candidate gene for dyslexia susceptibility.
References
Yoshida, T., et al. Int. J. Mol. Med. 24(2):233-246(2009)Couto, J.M., et al. J. Neurogenet. 22(4):295-313(2008)
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