|Other Names||Keratin, type I cytoskeletal 24, Cytokeratin-24, CK-24, Keratin-24, K24, Type I keratin-24, KRT24, KA24|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13368b was selected from the C-term region of KRT24. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Highly expressed in keratinocytes, placenta, colon and spleen. Expressed at lower level in thymus and testis|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the type I (acidic) keratinfamily, which belongs to the superfamily of intermediate filament(IF) proteins. Keratins are heteropolymeric structural proteinswhich form the intermediate filament. These filaments, along withactin microfilaments and microtubules, compose the cytoskeleton ofepithelial cells. The type I keratin genes are clustered in aregion of chromosome 17q12-q21.
Hong, Y., et al. Clin. Cancer Res. 13(4):1107-1114(2007)Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)Sprecher, E., et al. J. Invest. Dermatol. 119(3):692-698(2002)
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