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FRMD7 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6ZUT3 |
|---|---|
| Clone Names | 100318217 |
| Gene ID | 90167 |
|---|---|
| Other Names | FERM domain-containing protein 7, FRMD7 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13371a was selected from the N-term region of FRMD7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FRMD7 |
|---|---|
| Function | Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability. |
| Cellular Location | Cell projection, neuron projection {ECO:0000250|UniProtKB:A2AD83}. Cell projection, growth cone {ECO:0000250|UniProtKB:A2AD83}. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones (By similarity). {ECO:0000250|UniProtKB:A2AD83} |
| Tissue Location | Expressed in liver, kidney, pancreas and at low levels in brain and heart. Expressed in embryonic brain and developing neural retina. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mutations in this gene are associated with X-linkedcongenital nystagmus.
References
Fingert, J.H., et al. Ophthalmic Genet. 31(2):77-80(2010)Betts-Henderson, J., et al. Hum. Mol. Genet. 19(2):342-351(2010)He, X., et al. Genet. Test. 12(4):607-613(2008)Thomas, S., et al. Brain 131 (PT 5), 1259-1267 (2008) :Li, N., et al. Mol. Vis. 14, 733-738 (2008) :
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