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HS3ST1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O14792
Clone Names 100405062
Peptide ID 100405062
Additional Information
Gene ID 9957
Other Names Heparan sulfate glucosamine 3-O-sulfotransferase 1, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1, 3-OST-1, Heparan sulfate 3-O-sulfotransferase 1, h3-OST-1, HS3ST1, 3OST, 3OST1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13378b was selected from the C-term region of HS3ST1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HS3ST1
Synonyms 3OST, 3OST1
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
Cellular Location Golgi apparatus lumen.
Tissue Location Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta
Research Areas
Citations (0)

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Heparan sulfate biosynthetic enzymes are key components ingenerating a myriad of distinct heparan sulfate fine structuresthat carry out multiple biologic activities. The enzyme encoded bythis gene is a member of the heparan sulfate biosynthetic enzymefamily. It possesses both heparan sulfate glucosaminyl3-O-sulfotransferase activity, anticoagulant heparan sulfateconversion activity, and is a rate limiting enzyme for synthesis ofanticoagulant heparan. This enzyme is an intraluminal Golgiresident protein.


Lamesch, P., et al. Genomics 89(3):307-315(2007)Edavettal, S.C., et al. Biochemistry 43(16):4680-4688(2004)Hernaiz, M., et al. Biochem. Biophys. Res. Commun. 276(1):292-297(2000)Liu, J., et al. J. Biol. Chem. 274(8):5185-5192(1999)Shworak, N.W., et al. J. Biol. Chem. 274(8):5170-5184(1999)

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$ 80.00
Cat# BP13378b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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