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BNIP2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q12982 |
|---|---|
| Clone Names | 100324082 |
| Gene ID | 663 |
|---|---|
| Other Names | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, BNIP2, NIP2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13384b was selected from the C-term region of BNIP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BNIP2 |
|---|---|
| Synonyms | NIP2 |
| Function | Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. |
| Cellular Location | Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the BCL2/adenovirus E1B 19kd-interacting protein (BNIP) family. Though the specific functionis unknown, it interacts with the E1B 19 kDa protein which isresponsible for the protection of virally-induced cell death, aswell as E1B 19 kDa-like sequences of BCL2, also an apoptoticprotector.
References
Scott, G.B., et al. Biochem. J. 431(3):423-431(2010)Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Valencia, C.A., et al. Biochem. Biophys. Res. Commun. 364(3):495-501(2007)Zhou, Y.T., et al. Exp. Cell Res. 303(2):263-274(2005)Shang, X., et al. J. Biol. Chem. 278(46):45903-45914(2003)
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