|Other Names||BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, BNIP2, NIP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13384b was selected from the C-term region of BNIP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.|
|Cellular Location||Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the BCL2/adenovirus E1B 19kd-interacting protein (BNIP) family. Though the specific functionis unknown, it interacts with the E1B 19 kDa protein which isresponsible for the protection of virally-induced cell death, aswell as E1B 19 kDa-like sequences of BCL2, also an apoptoticprotector.
Scott, G.B., et al. Biochem. J. 431(3):423-431(2010)Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Valencia, C.A., et al. Biochem. Biophys. Res. Commun. 364(3):495-501(2007)Zhou, Y.T., et al. Exp. Cell Res. 303(2):263-274(2005)Shang, X., et al. J. Biol. Chem. 278(46):45903-45914(2003)
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