Thioredoxin 2 (Trx2) Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q99757 |
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Clone Names | 3121803 |
Gene ID | 25828 |
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Other Names | Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1338a was selected from the N-term region of human Trx2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TXN2 |
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Synonyms | TRX2 |
Function | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity. |
Cellular Location | Mitochondrion |
Tissue Location | Widely expressed in adult (at protein level) and fetal tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TRX2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
References
J. Biol. Chem. 277 (36), 33249-33257 (2002)J. Biol. Chem. 277 (36), 33242-33248 (2002)
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