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RPL3 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P39023
Clone Names 110111033
Additional Information
Gene ID 6122
Other Names 60S ribosomal protein L3, HIV-1 TAR RNA-binding protein B, TARBP-B, RPL3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13400c was selected from the Center region of RPL3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPL3
Function Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547, PubMed:35674491). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:32669547).
Cellular Location Nucleus, nucleolus. Cytoplasm
Research Areas
Citations (0)
citation

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Background

Ribosomes, the complexes that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L3P family of ribosomal proteins and it is located in thecytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it hasbeen suggested that the protein contributes to tat-mediatedtransactivation. This gene is co-transcribed with several smallnucleolar RNA genes, which are located in several of this gene'sintrons. Alternate transcriptional splice variants, encodingdifferent isoforms, have been characterized. As is typical forgenes encoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome. [provided byRefSeq].

References

Russo, A., et al. Biochim. Biophys. Acta 1799 (5-6), 419-428 (2010) :Rikova, K., et al. Cell 131(6):1190-1203(2007)Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Bergqvist, M., et al. Dis. Esophagus 19(1):20-23(2006)

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$ 277.78
Cat# BP13400c
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Availability: 2 weeks
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Ordering Information

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