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KLHL13 Antibody (N-term ) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9P2N7
Clone Names 100416043
Peptide ID 100416043
Additional Information
Gene ID 90293
Other Names Kelch-like protein 13, BTB and kelch domain-containing protein 2, KLHL13, BKLHD2, KIAA1309
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13407a was selected from the N-term region of KLHL13. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL13
Synonyms BKLHD2, KIAA1309
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
Research Areas
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This gene encodes a BTB and kelch domain containingprotein and belongs to the kelch repeat domain containingsuperfamily of proteins. The encoded protein functions as anadaptor protein that complexes with Cullin 3 and other proteins toform the Cullin 3-based E3 ubiquitin-protein ligase complex. Thiscomplex is necessary for proper chromosome segregation andcompletion of cytokinesis. Alternate splicing results in multipletranscript variants.


Sumara, I., et al. Cell Cycle 6(24):3004-3010(2007)Sumara, I., et al. Dev. Cell 12(6):887-900(2007)

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$ 80.00
Cat# BP13407a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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