|Other Names||Mirror-image polydactyly gene 1 protein, MIPOL1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13415c was selected from the Center region of MIPOL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed very weakly in heart, liver, skeletal muscle, kidney, pancreas and fetal kidney. Not detected in brain, placenta and lung.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a coiled-coil domain-containing protein.The encoded protein may function as a tumor suppressor. Atranslocation that results in truncation of the protein encoded bythis locus has been associated with mirror-image polydactyly, alsoknown as Laurin-Sandrow Syndrome. Alternatively spliced transcriptvariants have been described.
Cheung, A.K., et al. Proc. Natl. Acad. Sci. U.S.A. 106(34):14478-14483(2009)Kamnasaran, D., et al. Eur. J. Hum. Genet. 11(4):315-324(2003)Kondoh, S., et al. J. Hum. Genet. 47(3):136-139(2002)
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