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MIPOL1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TD10 |
|---|---|
| Clone Names | 100416229 |
| Gene ID | 145282 |
|---|---|
| Other Names | Mirror-image polydactyly gene 1 protein, MIPOL1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13415c was selected from the Center region of MIPOL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MIPOL1 |
|---|---|
| Tissue Location | Expressed very weakly in heart, liver, skeletal muscle, kidney, pancreas and fetal kidney. Not detected in brain, placenta and lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a coiled-coil domain-containing protein.The encoded protein may function as a tumor suppressor. Atranslocation that results in truncation of the protein encoded bythis locus has been associated with mirror-image polydactyly, alsoknown as Laurin-Sandrow Syndrome. Alternatively spliced transcriptvariants have been described.
References
Cheung, A.K., et al. Proc. Natl. Acad. Sci. U.S.A. 106(34):14478-14483(2009)Kamnasaran, D., et al. Eur. J. Hum. Genet. 11(4):315-324(2003)Kondoh, S., et al. J. Hum. Genet. 47(3):136-139(2002)
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