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KRT16 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P08779
Clone Names 100427087
Peptide ID 100427087
Additional Information
Gene ID 3868
Other Names Keratin, type I cytoskeletal 16, Cytokeratin-16, CK-16, Keratin-16, K16, KRT16, KRT16A
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13423c was selected from the Center region of KRT16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT16
Synonyms KRT16A
Function Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance.
Tissue Location Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts
Research Areas
Citations (0)

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The protein encoded by this gene is a member of thekeratin gene family. The keratins are intermediate filamentproteins responsible for the structural integrity of epithelialcells and are subdivided into cytokeratins and hair keratins. Mostof the type I cytokeratins consist of acidic proteins which arearranged in pairs of heterotypic keratin chains and are clusteredin a region of chromosome 17q12-q21. This keratin has beencoexpressed with keratin 14 in a number of epithelial tissues,including esophagus, tongue, and hair follicles. Mutations in thisgene are associated with type 1 pachyonychia congenita,non-epidermolytic palmoplantar keratoderma and unilateralpalmoplantar verrucous nevus.


Leung, M.C., et al. J. Proteome Res. 9(10):5153-5163(2010)Trost, A., et al. Mech. Ageing Dev. 131(5):346-353(2010)Gruber, R., et al. Br. J. Dermatol. 161(6):1391-1395(2009)Barcelos, A.C., et al. J. Cutan. Pathol. 36(6):647-654(2009)Wu, C., et al. Exp. Dermatol. 17(8):645-652(2008)

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$ 80.00
Cat# BP13423c
Availability: In Stock
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