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HMGB1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession P09429
Clone Names 100427100
Peptide ID 100427100
Additional Information
Gene ID 3146
Other Names High mobility group protein B1, High mobility group protein 1, HMG-1, HMGB1, HMG1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13425c was selected from the Center region of HMGB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMGB1
Synonyms HMG1
Function DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Cellular Location Nucleus. Chromosome.
Research Areas
Citations (0)

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Background

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).

References

Yujiri, T., et al. Eur. J. Haematol. 85(4):366-367(2010)Tang, D., et al. Oncogene 29(38):5299-5310(2010)He, X.C., et al. Zhonghua Gan Zang Bing Za Zhi 18(5):361-365(2010)Bao, G., et al. World J Surg Oncol 8 (1), 52 (2010) :Naumnik, W., et al. Folia Histochem. Cytobiol. 47(4):703-709(2009)

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$ 80.00
Cat# BP13425c
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