|Other Names||Nik-related protein kinase, NRK|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13448c was selected from the Center region of NRK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
The mouse ortholog of this gene encodes a protein kinaserequired for JNK activation. The encoded protein may be involved inthe induction of actin polymerization in late embryogenesis.
Ross, M.T., et al. Nature 434(7031):325-337(2005)Nakano, K., et al. Exp. Cell Res. 287(2):219-227(2003)
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