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TBCC Antibody (N-term ) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q15814
Clone Names 100416009
Peptide ID 100416009
Additional Information
Gene ID 6903
Other Names Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC, TBCC
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13475a was selected from the N-term region of TBCC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Cellular Location Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium
Tissue Location Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level).
Research Areas
Citations (0)

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Cofactor C is one of four proteins (cofactors A, D, E, andC) involved in the pathway leading to correctly folded beta-tubulinfrom folding intermediates. Cofactors A and D are believed to playa role in capturing and stabilizing beta-tubulin intermediates in aquasi-native confirmation. Cofactor E binds to the cofactorD/beta-tubulin complex; interaction with cofactor C then causes therelease of beta-tubulin polypeptides that are committed to thenative state.


Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010) :Nature 447(7145):661-678(2007)Mungall, A.J., et al. Nature 425(6960):805-811(2003)Bartolini, F., et al. J. Biol. Chem. 277(17):14629-14634(2002)Tian, G., et al. Cell 86(2):287-296(1996)

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$ 80.00
Cat# BP13475a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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