KCNS2 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9ULS6 |
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Clone Names | 100416109 |
Gene ID | 3788 |
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Other Names | Potassium voltage-gated channel subfamily S member 2, Delayed-rectifier K(+) channel alpha subunit 2, Voltage-gated potassium channel subunit Kv92, KCNS2, KIAA1144 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13489a was selected from the N-term region of KCNS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | KCNS2 |
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Synonyms | KIAA1144 |
Function | Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:O35174}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O35174}. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2 {ECO:0000250|UniProtKB:O35174} |
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Provided below are standard protocols that you may find useful for product applications.
Background
KCNS2 is potassium channel subunit. It modulates channel activity and reduces the ion flow (By similarity).
References
Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)Salinas, M., et al. J. Biol. Chem. 272(39):24371-24379(1997)Banfi, S., et al. Nat. Genet. 13(2):167-174(1996)
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