|Other Names||Calcium-binding protein 5, CaBP5, CABP5, CABP3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13491a was selected from the N-term region of CABP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to a subfamily of calciumbinding proteins, which share similarity to calmodulin. Calciumbinding proteins are an important component of calcium mediatedcellular signal transduction. Expression of this gene isretina-specific. The mouse homolog of this protein has been shownto express in the inner nuclear layer of the retina, suggested itsrole in neuronal functioning. The specific function of this gene isunknown.
Haeseleer, F., et al. Biochem. Biophys. Res. Commun. 290(2):615-623(2002)Haeseleer, F., et al. J. Biol. Chem. 275(2):1247-1260(2000)
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