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CABP5 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NP86
Clone Names 100416111
Peptide ID 100416111
Additional Information
Other Names Calcium-binding protein 5, CaBP5, CABP5, CABP3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13491a was selected from the N-term region of CABP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CABP5
Synonyms CABP3
Function Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals (By similarity).
Cellular Location Cytoplasm.
Tissue Location Retina.. EMBL; AF170815; AAF25798.1; -; Genomic_DNA EMBL; AF170812; AAF25798.1; JOINED; Genomic_DNA EMBL; AF170813; AAF25798.1; JOINED; Genomic_DNA EMBL; AF170814; AAF25798.1; JOINED; Genomic_DNA EMBL; AF169159; AAF25793.1; -; mRNA EMBL; BC126133; AAI26134.1; -; mRNA EMBL; BC126135; AAI26136.1; -; mRNA CCDS; CCDS12709.1; - RefSeq; NP_062829.1; NM_019855.4 UniGene; Hs.117694; - ProteinModelPortal; Q9NP86; - SMR; Q9NP86; - BioGrid; 121142; 8 IntAct; Q9NP86; 29 STRING; 9606.ENSP00000293255; - PhosphoSitePlus; Q9NP86; - BioMuta; CABP5; - DMDM; 13431356; - PaxDb; Q9NP86; - PeptideAtlas; Q9NP86; - PRIDE; Q9NP86; - ProteomicsDB; 81931; - DNASU; 56344; - Ensembl; ENST00000293255; ENSP00000293255; ENSG00000105507 GeneID; 56344; - KEGG; hsa:56344; - UCSC; uc002phu.3; human CTD; 56344; - EuPathDB; HostDB:ENSG00000105507.2; - GeneCards; CABP5; - HGNC; HGNC:13714; CABP5 HPA; HPA043698; - MIM; 607315; gene neXtProt; NX_Q9NP86; - OpenTargets; ENSG00000105507; - PharmGKB; PA26004; - eggNOG; KOG0027; Eukaryota eggNOG; COG5126; LUCA GeneTree; ENSGT00760000118901; - HOGENOM; HOG000233018; - HOVERGEN; HBG012180; - InParanoid; Q9NP86; - OMA; AFNEFDK; - OrthoDB; EOG091G0PB4; - PhylomeDB; Q9NP86; - TreeFam; TF334804; - GenomeRNAi; 56344; - PRO; PR:Q9NP86; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000105507; - CleanEx; HS_CABP5; - Genevisible; Q9NP86; HS GO; GO:0005829; C:cytosol; IDA:MGI GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB GO; GO:0007165; P:signal transduction; NAS:UniProtKB CDD; cd00051; EFh; 1 InterPro; IPR011992; EF-hand-dom_pair InterPro; IPR018247; EF_Hand_1_Ca_BS InterPro; IPR002048; EF_hand_dom Pfam; PF13499; EF-hand_7; 2 SMART; SM00054; EFh; 3 SUPFAM; SSF47473; SSF47473; 1 PROSITE; PS00018; EF_HAND_1; 3 PROSITE; PS50222; EF_HAND_2; 4 1: Evidence at protein level; Calcium; Complete proteome; Cytoplasm; Metal-binding; Polymorphism; Reference proteome; Repeat CHAIN 1 173 Calcium-binding protein 5 /FTId=PRO_0000073524 DOMAIN 28 63 EF-hand 1. {ECO:0000255|PROSITE- ProRule:PRU00448} DOMAIN 64 99 EF-hand 2. {ECO:0000255|PROSITE- ProRule:PRU00448} DOMAIN 105 140 EF-hand 3. {ECO:0000255|PROSITE- ProRule:PRU00448} DOMAIN 142 173 EF-hand 4. {ECO:0000255|PROSITE- ProRule:PRU00448} CA_BIND 41 52 1. {ECO:0000255|PROSITE- ProRule:PRU00448} CA_BIND 118 129 2. {ECO:0000255|PROSITE- ProRule:PRU00448} CA_BIND 155 166 3. {ECO:0000255|PROSITE- ProRule:PRU00448} VARIANT 65 65 T -> R (in dbSNP:rs34862923) /FTId=VAR_033695 VARIANT 80 80 L -> P (in dbSNP:rs8105198) /FTId=VAR_048633 VARIANT 128 128 V -> A (in dbSNP:rs3745746) /FTId=VAR_020020 VARIANT 140 140 E -> K (in dbSNP:rs34681062) /FTId=VAR_048634 VARIANT 147 147 I -> S (in dbSNP:rs10425606) /FTId=VAR_048635 SEQUENCE 173 AA; 19826 MW; BB4DD28E9ECC55AF CRC64; MQFPMGPACI FLRKGIAEKQ RERPLGQDEI EELREAFLEF DKDRDGFISC KDLGNLMRTM GYMPTEMELI ELGQQIRMNL GGRVDFDDFV ELMTPKLLAE TAGMIGVQEM RDAFKEFDTN GDGEITLVEL QQAMQRLLGE RLTPREISEV VREADVNGDG TVDFEEFVKM MSR
Research Areas
Citations (0)

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Background

The product of this gene belongs to a subfamily of calciumbinding proteins, which share similarity to calmodulin. Calciumbinding proteins are an important component of calcium mediatedcellular signal transduction. Expression of this gene isretina-specific. The mouse homolog of this protein has been shownto express in the inner nuclear layer of the retina, suggested itsrole in neuronal functioning. The specific function of this gene isunknown.

References

Haeseleer, F., et al. Biochem. Biophys. Res. Commun. 290(2):615-623(2002)Haeseleer, F., et al. J. Biol. Chem. 275(2):1247-1260(2000)

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$ 80.00
Cat# BP13491a
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