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POU3F3 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P20264
Clone Names 100416125
Peptide ID 100416125
Additional Information
Gene ID 5455
Other Names POU domain, class 3, transcription factor 3, Brain-specific homeobox/POU domain protein 1, Brain-1, Brn-1, Octamer-binding protein 8, Oct-8, Octamer-binding transcription factor 8, OTF-8, POU3F3, BRN1, OTF8
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13495c was selected from the Center region of POU3F3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU3F3
Synonyms BRN1, OTF8
Function Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met- mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity).
Cellular Location Nucleus.
Tissue Location Brain.
Research Areas
Citations (0)

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POU3F3 is a member of the class III POU family oftranscription factors (see POU3F1; MIM 602479) that are expressedin the central nervous system. The POU domain in these proteins isrequired for high affinity binding to octamer DNA sequences(summarized by Sumiyama et al., 1996 [PubMed 8703082]).[supplied byOMIM].


Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)Kuhlbrodt, K., et al. J. Biol. Chem. 273(26):16050-16057(1998)Sumiyama, K., et al. Mamm. Genome 9(2):180-181(1998)Malik, K.F., et al. Brain Res. Mol. Brain Res. 45(1):99-107(1997)Sumiyama, K., et al. J. Mol. Evol. 43(3):170-178(1996)

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$ 80.00
Cat# BP13495c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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