|Other Names||Keratin, type I cuticular Ha7, Hair keratin, type I Ha7, Keratin-37, K37, KRT37, HHA7, HKA7, KRTHA7|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13514c was selected from the Center region of KRT37. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||HHA7, HKA7, KRTHA7|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of thekeratin gene family. As a type I hair keratin, it is an acidicprotein which heterodimerizes with type II keratins to form hairand nails. The type I hair keratins are clustered in a region ofchromosome 17q12-q21 and have the same direction of transcription.
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)Rogers, M.A., et al. Differentiation 72 (9-10), 527-540 (2004) :Langbein, L., et al. J. Biol. Chem. 274(28):19874-19884(1999)Rogers, M.A., et al. J. Biol. Chem. 273(41):26683-26691(1998)Yu, J., et al. J. Invest. Dermatol. 101 (1 SUPPL), 56S-59S (1993) :
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