CASS4 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NQ75 |
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Clone Names | 100416240 |
Gene ID | 57091 |
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Other Names | Cas scaffolding protein family member 4, HEF-like protein, HEF1-EFS-p130Cas-like protein, HEPL, CASS4, C20orf32, HEFL |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13515b was selected from the C-term region of CASS4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CASS4 |
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Synonyms | C20orf32, HEFL |
Function | Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. |
Cellular Location | Cytoplasm, cytoskeleton. Cell junction, focal adhesion |
Tissue Location | Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines |
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Provided below are standard protocols that you may find useful for product applications.
Background
Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.
References
Singh, M.K., et al. Mol. Biol. Cell 19(4):1627-1636(2008)Rikova, K., et al. Cell 131(6):1190-1203(2007)Deloukas, P., et al. Nature 414(6866):865-871(2001)
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