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CD3E Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P07766
Clone Names 100427002
Peptide ID 100427002
Additional Information
Gene ID 916
Other Names T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13531b was selected from the C-term region of CD3E. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD3E
Synonyms T3E
Function The CD3 complex mediates signal transduction.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, andthe T-cell receptor alpha/beta and gamma/delta heterodimers, formsthe T-cell receptor-CD3 complex. This complex plays an importantrole in coupling antigen recognition to several intracellularsignal-transduction pathways. The genes encoding the epsilon, gammaand delta polypeptides are located in the same cluster onchromosome 11. The epsilon polypeptide plays an essential role inT-cell development. Defects in this gene cause immunodeficiency.This gene has also been linked to a susceptibility to type Idiabetes in women.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Brophy, K., et al. BMC Med. Genet. 11, 76 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Su, Z., et al. Int. J. Mol. Med. 24(4):437-444(2009)

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$ 80.00
Cat# BP13531b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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